Biological tissues are compliant, dynamic, and structurally complex. Their mechanical properties are not a mere byproduct, but a regulator, of how cells proliferate, differentiate, migrate, and signal. In both health and disease, the mechanical microenvironment shapes cellular behavior, yet a clear, quantitative understanding of how mechanics are maintained at interfaces, influence cell function, and interact with interventions remains incomplete.

Our group investigates the mechanics of soft biological matter, with a focus on living cells and tissues in the multi-organ female reproductive tract, in particular, the fallopian tubes and the uterus. Using high-resolution biomechanical measurements—Brillouin microscopy, atomic force microscopy (AFM), and rheology—we study how physical signals arise, propagate, and change over time.

We are particularly interested in spatiotemporal heterogeneity at tissue interfaces, and how mechanical properties modulate transport, barrier function, wound repair, and dysfunction. We study how cells decode these cues and actively reshape their surroundings in response. By developing a quantitative, experimentally grounded perspective, we aim to define fundamental principles of mechanical regulation in reproductive tissues.

Our long-term goal is translation. We aim to develop benchmarks, biomarkers, and standardized measurement protocols that enable cross-study comparison and support mechanics-aware research and care.