Prof. Miki Ebisuya
TU Dresden

Abstract
Different animal species exhibit distinct developmental timing and morphology. For example, human embryonic development proceeds 2-3 times more slowly than in mice, and the human brain undergoes markedly greater expansion compared to other species. Our group investigates the mechanisms underlying these species-specific differences using in vitro models derived from the “Stem Cell Zoo,” a collection of pluripotent stem cells from a wide range of mammalian species. In this talk, I will present our findings on species-specific segmentation clock periods and brain tissue mechanics, highlighting how the Stem Cell Zoo platform enables comparative analysis of developmental tempo and biophysical parameters across species. 
Refs:
Matsuda et al, Science, 369, 1450-1455 (2020)
Lazaro et al, Cell Stem Cell, 30, 938-949 (2023)
Xu et al, bioRxiv, doi: 10.1101/2025.10.07.680907 (2025)
Marchenko et al, bioRxiv, doi: 10.64898/2026.03.30.715222 (2026)

Biography
Miki Ebisuya did her undergraduate and PhD research at Kyoto University, Japan. After getting her PhD in 2008, she became a group leader at Kyoto University in 2009. Her lab moved to RIKEN in 2013, to the European Molecular Biology Laboratory (EMBL) Barcelona in 2018, and finally to Physics of Life (PoL), Technical University Dresden (TU Dresden) in 2023. Her research group focuses on recapitulating developmental processes using the stem cell zoo, a collection of pluripotent stem cells from various mammalian species.

Location
Seminar Room, 0.125, Kussmaulallee 2
Location Details

Zoom
https://eu02web.zoom-x.de/j/63317851952?pwd=LfaTRrHfSCHWZQQxafGkrhAUeanRap.1
Meeting-ID: 633 1785 1952
Kenncode: 536306