Prof. A.R. Bausch
Center for functional Protein Assemblies (CPA), Chair for Cellular Biophysics
Technical University Munich

Abstract
Living matter relies on the self organization of its components into higher order structures, on the molecular as well as on the cellular, organ or even organism scale. Collective motion due to active transport processes has been shown to be a promising route for attributing fascinating order formation processes on these different length scales. Here I will present recent results on structure formation in organoid systems, demonstrating how mechanical feedback between extracellular matrix, proliferation and cell migration drives structure formation process in these multicellular model systems. I will present results on the developmental phase of mammary gland, pancreatic ducal adenocarcinoma organoids and epiblastoid development. 

Biography
Prof. Andreas Bausch is the Founding Director of the Center of Organoid Systems (COS) and the Center for Functional Protein Assemblies at the Technical University of Munich (TUM), Germany. In July 2025, he was awarded the endowed Hein Heinz Nixdorf Chair Professorship in Biophysical Engineering of Living Matter at TUM.

He studied physics at TUM and the Université de Montréal and received his doctorate from TUM in 1999. An Emmy Noether Fellowship allowed him to work at Harvard University under Prof. D. Weitz. After receiving several global invitations, he accepted the Chair of Cellular Biophysics at TUM in 2008 and is currently a member of the Senate and the Academic Board of Trustees at TUM.

Internationally recognized for his contributions, Prof. Bausch has received multiple honors and held leadership roles at major academic institutions and events, including a Visiting Scholarship at Harvard in 2021 and the Visiting Miller Professor Appointment at the University of California, Berkeley, in 2015. 

Prof. Bausch conducts research on structure formation in biological systems, focusing on the mechanical properties of the cytoskeleton and the self-organization of organoid structures. His transdisciplinary approach has led to significant breakthroughs reaching from our understanding cytoskeletal function, cell mechanics, biosensors up to the complex branching morphogenesis in organoids.

Utilizing advanced technologies such as microfluidics, multimodal imaging, AI-guided microscopy, magnetic and optical tweezers, and atomic force microscopy, his research team aims to uncover the fundamental principles driving organoid development, contributing to advancements in developmental biology and tissue engineering. His recent efforts focus on translating these findings into biotechnological applications.

Location
Seminar Room, 0.125, Kussmaulallee 2
Location Details